Microneedle-Array Patch with Enzyme-Free Polymeric Components for On-Dem...

An electronics-free, enzyme-free, and nanoparticle-free smart artificial on-skin pancreas, which is a hybrid microneedle-array patch fabricated with a glucose-sensitive boronate-hydrogel and biocompatible silk fibroin semi-interpenetrating network, able to continuously monitor glucose levels whilst autonomously delivering insulin on demand. This microneedles-array patch offers long-acting persistent glycemic control in a safe, convenient, and painless way, which will significantly improve patients’ life quality.

This is reported by Siyuan Chen, Hiroko Matsumoto, Yuki Moro-oka, Miyako Tanaka, Yuji Miyahara, Takayoshi Suganami, and Akira Matsumoto in their article here: https://doi.org/10.1002/adfm.201807369.

To learn more, please go to the Advanced Functional Materials homepage.